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Gliclazide and Metformin Hydrochloride are combined in certain medications to manage type 2 diabetes. It’s important to note that these medications should only be taken under the guidance of a healthcare professional, as they can have significant effects on blood sugar levels and overall health.

Gliclazide 30 mg:

  • Gliclazide: Gliclazide is an oral hypoglycemic agent, part of the sulfonylurea class of medications, used to lower blood sugar levels in people with type 2 diabetes.

Metformin Hydrochloride 500 mg:

  • Metformin Hydrochloride: Metformin is an oral antidiabetic medication that helps control blood sugar levels by improving insulin sensitivity and reducing the production of glucose by the liver.


  1. Type 2 Diabetes: The combination of gliclazide and metformin is often prescribed to manage type 2 diabetes, especially when diet and exercise alone are not sufficient to control blood sugar levels.

Problems and Concerns:

  1. Hypoglycemia: Gliclazide can cause low blood sugar levels (hypoglycemia), which can lead to symptoms like dizziness, confusion, shakiness, and even fainting. It’s important to monitor blood sugar levels regularly and follow your healthcare provider’s recommendations to prevent hypoglycemia.
  2. Gastrointestinal Upset: Metformin can sometimes cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal discomfort. These side effects may improve over time or with dose adjustments.
  3. Drug Interactions: These medications can interact with other drugs, potentially impacting their effectiveness or causing adverse effects. Inform your healthcare provider about all medications you are taking.
  4. Lactic Acidosis (Rare): Metformin, if not used appropriately, can lead to a rare but serious condition called lactic acidosis, which is characterized by the buildup of lactic acid in the bloodstream. This condition requires immediate medical attention.
  5. Individual Response: The effectiveness of this combination can vary from person to person. Blood sugar levels should be closely monitored to ensure they are well controlled.
  6. Dosage and Titration: Dosage adjustments may be necessary over time to achieve optimal blood sugar control.
  7. Kidney Function: Both gliclazide and metformin are processed by the kidneys. If you have kidney impairment, your healthcare provider will determine whether these medications are suitable for you and at what doses.
  8. Liver Function: Gliclazide is metabolized by the liver. Individuals with liver problems may need dosage adjustments.
  9. Underlying Conditions: Addressing other health conditions, such as cardiovascular health, is crucial in diabetes management.
  10. Pregnancy and Lactation: Diabetes management during pregnancy and lactation requires special attention. Consult a healthcare provider before using these medications in these situations.

Consultation with Healthcare Provider:

If you are prescribed gliclazide 30 mg and metformin hydrochloride 500 mg tablets, consult a healthcare provider. They can assess your diabetes management needs, discuss potential benefits and risks, and guide you on the proper dosage and duration of use. Regular follow-up appointments and blood sugar monitoring are important for effective diabetes management and to address any concerns that may arise during the course of treatment. If you experience severe side effects or adverse reactions, seek medical attention immediately.

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